"Arequipa: We regret the death of a person during clashes on the Añashuayco bridge, a road located in the north of the city. We ask the Peruvian Prosecutor's Office for a prompt investigation of the facts to determine responsibilities," the entity said.
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It added that ten people were injured and taken to health centers in the area.
Protests were taking place in several cities of the country following a call for a national strike.
In the country's capital, Lima, thousands of people were protesting for the resignation of President Dina Boluarte and several clashes with the police were reported.
Since December 10, several social protests have been taking place in Peru by citizen groups and organizations, demanding the resignation of Boluarte, appointed after the Congress dismissed her predecessor, Pedro Castillo (2021-2022), as well as the immediate call for early elections.
Until Wednesday afternoon, the Ombudsman's Office reported the death of 50 civilians in clashes with security forces, traffic accidents and blockades linked to the mobilizations, and one policeman who reportedly died as a result of violence by demonstrators.